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Cyclopenta[a]-phenanthrenes (Cambridge Monographs on Cancer Research) by Maurice M. Coombs

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Published by Cambridge University Press .
Written in English

Subjects:

  • Oncology,
  • Derivatives,
  • Medical / Oncology,
  • Carcinogens,
  • DNA,
  • metabolism,
  • Cyclopentaphenanthrene,
  • Carcinogenesis

Book details:

The Physical Object
FormatHardcover
Number of Pages288
ID Numbers
Open LibraryOL7736119M
ISBN 100521301238
ISBN 109780521301237

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Silvestrol is a natural product from the flavagline family, with a cyclopenta[b]benzofuran core structure and an unusual dioxane ether side chain, which is found in the bark of trees from the genus Aglaia, especially Aglaia silvestris and Aglaia foveolata.. Bioactivity. It acts as a potent and selective inhibitor of the RNA helicase enzyme eIF4A, and has both broad-spectrum antiviral . PubChem is the world's largest collection of freely accessible chemical information. Search chemicals by name, molecular formula, structure, and other identifiers. Find chemical and physical properties, biological activities, safety and toxicity information, patents, . ONX (BGC ) is an experimental drug that has been developed to target ovarian cancer. It is a folate receptor alpha mediated thymidylate synthase inhibitor.. ONX was originally developed by BTG and the Institute of Cancer Research in the UK, and subsequently licensed to Onyx Pharmaceuticals for clinical development. It is designed to selectively target tumour CAS Number: , . We survey the emerging class of planar cyclopenta‐fused polycyclic arenes (CPPAs). Typically viewed as reactive anti‐aromatic species, new synthetic methods and rational design have allowed researchers to create unprecedented structures and study their unique by: 4.

Scholarly Articles and Book Chapters. Deposit a peer-reviewed article or book chapter. If you would like to deposit a poster, presentation, conference paper or white paper, use the “Scholarly Works” deposit : Denise L. Matthews. Soumyajit Das, Sanjio S Zade: Poly(cyclopenta[c]selenophene): a new polyselenophene. Chemical Communications , 46, Book Chapters: 1. "Open-shell benzenoid polycyclic hydrocarbons" by Soumyajit Das, Jishan Wu, in a book entitled 'Polycyclic Arenes and Heteroarenes: Synthesis, Properties, and Applications', Editor. Natural products have long been an important source for the discovery of biologically active compounds, in particular, drug leads. Delavatine A (1), a structurally unusual cyclopenta[de]isoquinoline alkaloid, was isolated from Incarvillea ive spectroscopic analysis, in combination with biogenetic speculation, established the structure of 1. All except cyclopenta[a]phenanthrene have the numbering explicitly depicted (in P or P; anthracene and phenanthrene in errata). It's natural and expected that there can be different numberings for the same compound for different naming system chosen (e.g. decahydronaphthalene vs bicyclo[]decane – fusion carbons C-4a and C.

Cyclopenta(cd)pyrene (CPP; Fig. 1, I) is a highly mutagenic and carcinogenic non-alternant polycyclic aromatic hydrocarbon (PAH) without a bay region ().The high degree of localization and chemical reactivity of the C()-C() bond () suggested to us that it would be a likely site for enzymatic epoxidation yielding the 3,4-oxide (Fig. 1, II) as a primary : Eric Eisenstadt, Avram Gold. Natural occurrence, synthesis, chemical behavior, and physical properties of aromatic cyclopenta[c]pyrans are reviewed. Various strategies for the synthesis of cyclopenta[c]pyrans . 1 Naming and Indexing of Chemical Substances for Chemical Abstracts NAMING AND INDEXING OF CHEMICAL SUBSTANCES Foreword. Although the account which follows describes in consid-erable detail the selection of substance names for Chemical Abstracts (CA) in-dexes, it is not a nomenclature manual. It has the more restricted aim ofFile Size: 2MB. Cycloprovera | C50H70O7 | CID - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety.